Sant'Erasmo is the largest island in the Venice lagoon, though it is better known for its agriculture than its architecture. The so-called “countryside” of Venice, Sant'Erasmo is sparsely populated and the land is largely used to grow produce like peas, asparagus, figs, and the island's famous violet artichokes: these mineral-rich fruits and vegetables are then sold at the buzzing Rialto market in Venice. This is a great place to get away from the hustle of Venice and enjoy a picnic or bike ride through the island's picturesque roads.

It may be hard to imagine a wild, eco-sustainable island thriving in the Venice Lagoon, but Santa Cristina it's just that. This private island hotel, only accessible to guests staying at the resort, offers an exclusive natural experience for those lucky enough to visit: the island boasts fishing ponds, orchards, vineyards, and wild animals such as peacocks, pheasants, and pink flamingos. The island retreat is owned by a family who have infused the property with their passion for sustainability, organic living.

Surrounded by cypress trees and pines and dominated by a 13th-century Franciscan monastery, San Francesco del Deserto is an idyllic refuge in the Venice Lagoon. It is named for San Francesco d'Assisi, who spent time on the island in the year 1220, and is home to a handful of friars who reside in the monastery and offer tours of the grounds and two cloisters. The island is accessible only by private transport, so it's best to organize a boat excursion departing from nearby Burano.